Asian Journal of Mathematics & Statistics1994-54182077-2068Asian Network for Scientific Information10.3923/ajms.2014.21.28+/K^{+} Pump and Na^{+}/Ca^{2+} Exchanger on Calcium Distribution in Oocytes in Presence of Buffers]]>Ahmad NaikParvaizRaj PardasaniKamal1201471Calcium, a second messenger for signal transduction in cells plays an important role in almost every cell of our human body. In oocytes calcium plays a significant role in oocyte maturation. In the process of reproduction calcium concentration is regulated at high levels in oocytes through various mechanisms so as to meet the requirements of oocytes maturation. Thus modelling of calcium distribution in oocytes can help us in understanding this mechanism in a better way. Here an attempt has been made to develop a finite element model to study calcium distribution in oocytes. The model incorporates the parameters like diffusion coefficient, Na^{+}/K^{+} pump, Na^{+}/Ca^{2+} exchanger and buffers like BAPTA and EGTA. The proposed model is solved numerically using appropriate initial and boundary conditions. The program has been developed in MATLAB 7.10 for the entire problem and simulated on a 64 bit machine to compute the numerical results.]]>Morris, C.E.,2011Clarke, R.J. and D.J. Kane,2007Neher, E.,19732+ in the presence of cells presumed to be GLIA in cerebral cortex of cat.]]>Jha, B.K., N. Adlakha and M.N. Mehta,2013Jha, B.K., N. Adlakha and M.N. Mehta,20112+ channels on cytosolic calcium advection diffusion.]]>Keener, J. and J. Sneyd,1998Panday, S. and K.R. Pardasani,20132+ distribution in oocytes.]]>Panday, S. and K.R. Pardasani,2013+/Ca^{2+} exchanger on Ca^{2+} distribution in oocytes.]]>Naik, P.A. and K.R. Pardasani,20132+ channels on calcium distribution in oocytes for one dimensional unsteady state case.]]>Palty, R., W.F. Silverman, M. Hershfinkel, T. Caporale and S.L. Sensi et al.,2010+/Ca^{2+} exchange.]]>Lee, S.H., M.H. Kim, K.H. Park, Y.E. Earm and W.K. Ho,2002+-dependent Na^{+}/Ca^{2+} exchanger is a major Ca^{2+} clearance mechanism in axon terminals of rat neurohypophysis.]]>Rao, S.S.,2004Sherman, A., G.D. Smith, L. Dai and R.M. Miura,2001Smith, G.D.,19962+ channel.]]>Tewari, S.G.,2009Tewari, S.G.,2012Tewari, S.G. and K.R. Pardasani,2008+ influx on cytosolic Ca^{2+} diffusion.]]>